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Laboratory for Computational Biology and Bioinformatics
Research Objective:
The design, development, implementation, and testing of
high-performance computational solutions for complex discrete
optimization problems in computational biology, especially those
arising in the reconstruction of evolution from molecular
data.
News:
- November 10, 2009 
Congratulations to Dr. Krister Swenson, who successfully defended
his dissertation this afternoon, in the presence of jury members
Profs. Babak Falsafi (EPFL, jury president), Anastasia Ailamaki (EPFL),
Marie-France Sagot (U. Lyon and INRIA), David Sankoff (U. Ottawa),
and Bernard Moret. The jury unanimously nominated the work for the
annual EPFL Dissertation Award.
- October 2009 
Cristina Ghiurcuta has joined our lab, completing our team for this
coming academic year. All of us at the lab are involved in the
Advanced Algorithms course for this fall, Nishanth and Cristina
taking the course, Bernard teaching it, and Vaibhav, Wei, Xiuwei,
Yann, and Yu working as TAs for it.
- September 2009 
New faces, and missing old friends... Oana Jurj completed her summer
in our lab and returned to Timisoara, where she will start her MS
program; she leaves behind many friends and will be missed.
Krister Swenson left for Canada to start his postdoctoral studies
with David Sankoff at the University of Ottawa (and with Anne Bergeron
at the University of Montreal). We are all desolate -- Krister made
a lot of friends, had assumed quiet leadership in the lab, and had been
working with Bernard Moret since 2002 in New Mexico (learning how to
rock climb with him). We are also very proud of what Krister has
achieved and looking forward to continue working with him.
He will return for 10 days in early November for the formal defense of
his Ph.D. and suitable festivities!
Fortunately, in this time of separation, we were delighted to welcome
Nishanth Nair to our lab. Nishanth arrived on Sept. 14 and is already
a familiar figure in the lab. Cristina Ghiurcuta will arrive at the end
of the month and complete our new roster.
- July 2009
We are very happy to report that Cristina Ghiurcuta and Nishanth Nair
will join the EPFL PhD program this fall and work in our lab.
Cristina is completing her MS at the University of Timisoara
in Romania, while Nishanth finished his MS at the Indian Institute of
Science in Bangalore and is currently working for Microsoft Research.
We are looking forward to welcoming them both in the lab this fall.
- June 1, 2009
Ms. Oana Jurj joins our laboratory for a 3-month research summer;
she is finishing her degree at the University of Timisoara in
Romania and is interested in machine learning.
- September 2008
New postdoctoral fellow Wei Xu joins our group. Wei earned his BS
degree in physics from Nanjing U. in China, then left for Canada where
he earned an MS degree, also in physics, from McMaster U.; he
recently completed his PhD in discrete mathematics at the U. of Ottawa,
under the direction of Prof. David Sankoff. His research interests
revolve around models and algorithms for genomic rearrangements.
- June 2008
Jijun Tang, past PhD student of Bernard Moret as well as a lab
co-author and collaborator (and recent visitor), was tenured and
promoted at the University of South Carolina. Congratulations!
- February 2008
New Ph.D. student Vaibhav Rajan joins our group. Vaibhav
earned his BS at the Birla Institute of Technology and Science (BITS)
in Pilani, India, and just completed his MS degree at EPFL. His main
research interest is algorithm design.
- December 5, 2007
We are very proud to report that postdoctoral fellow Alexandros
Stamatakis received a prestigious Emmy
Noether award. This award will support Alexandros and a research
group of his own for the next five years at a German university -- an
ideal start for an academic career. Our heartfelt congratulations to
Alexis!
- October 15, 2007
Congratulations to Thomas Turnherr, who successfully defended his
MS thesis, on classification of stem cell populations; Thomas did
his work in Singapore in the A Star research laboratories. We wish
him well in his future endeavors.
- September 3, 2007
Congratulations to Maryam Zaheri and to Masoud Alipour, who both
successfully defended their MS theses. Maryam's thesis was on
the use of phylogenetic information in improving the inference of
transcriptional regulatory networks, while Masoud's was a study of
various methods for speeding up phylogenetic bootstrapping,
in particular how to determine when enough resampling has been done.
Maryam will start work on her Ph.D. this fall in Nicolas Salamin's
group at UNIL.
- August 2007
New Ph.D. student Yu Lin joins our group. Yu earned his BS at
the University of Science and Technology China and his MS at the
Chinese Academy of Sciences in the Institute of Computing Technology.
He also spent 9 months as an RA at the City University of Hong Kong.
He has worked in bicriteria optimization and computational biology.
- February 2007
New Ph.D. student Yann Christinat, back from a stay at Siemens
Princeton lab where he completed his MS thesis, joins our group.
His interests are in DNA sequence analysis, in particular sequence-based
domain identification.
MS student Masoud Alipour will do his MS thesis in our lab and work
part-time with Alexis Stamatakis as a programming assistant.
- November 2006
We have moved to our new quarters (INJ 230-1-2 and INJ 211); many
thanks to Professor Spaccapietra for his gracious hospitality. We are
looking forward to collaborations with his group in the area of
database research for bioinformatics.
- July 2006
Postdoctoral fellow Alexandros Stamatakis, the author of RaxML,
currently the fastest software for maximum likelihood inference of
phylogenies from nucleotide sequences, and new Ph.D. student Xiuwei
Zhang, who earned her MS from TsingHua University and is interested
in learning and statistical approaches, join our laboratory.
- June 2006
The laboratory opens (in principle) with the arrival from the USA of
Professor Moret and Ph.D. student Krister Swenson.
Open Positions:
We are always looking
for another Ph.D. student or postdoc.
Prerequisites for an RA position are a BS or (preferably) MS degree
in Computer Science or an MS in any of Mathematics, Biology, Physics,
and Biochemistry, with a strong background in computing and theory.
Applicants for a postdoc should have a PhD in Computer Science
or closely related area, a good working knowledge of some area of
bioinformatics, and a strong record of publication from their
Ph.D. work. A predilection for algorithm
development, programming, simulation, and testing is a big plus.
We also have projects
for MS students (I&C or Life Sciences).
Contact:
Send email to Professor Moret (bernard.moret@epfl.ch).
Addenda:
This lab is a Microsoft-free zone -- all of our machines run Linux.
If you are curious why,
KMFMS (among
many similar sites) has made a good, if somewhat dated (and certainly
not comprehensive), list of the technical, sociological, moral,
and other reasons why Microsoft is among the worst things that
happened to computing.
For a humorous and fast-reading account of OS development,
as well as another take on the Microsoft empire and its
competition, you should definitely read "In The Beginning There
Was The Command Line", by Neal Stephenson (widely available online).
The pages on this site are best viewed with Mozilla (and its
derivatives, such as Camino, Epiphany, Firefox, Galeon, Iceape,
Seamonkey, or Iceweasel) or Safari. We are using two of Microsoft's
MSTT free fonts (Impact and Trebuchet), which Microsoft's own IE,
ironically, cannot render well, especially at small sizes.
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